Not only strangers, but even appreciative friends, exhibit a particular kind of behavior towards us.

This couplet speaks about a deep sense of disappointment. The poet laments that let alone others, even those who are considered appreciative and understanding friends are treating them poorly or behaving in a way that causes pain. It's a poignant reflection on how sometimes, the very people we expect support from end up hurting us the most, leaving us feeling alone and betrayed. It highlights the pervasive nature of unkindness, where even close bonds aren't immune to hurtful conduct.